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The Chlamydia trachomatis secreted effector TmeA hijacks the N-WASP-ARP2/3 actin remodeling axis to facilitate cellular invasion

As an obligate intracellular pathogen, host cell invasion is paramount to Chlamydia trachomatis proliferation. While the mechanistic underpinnings of this essential process remain ill-defined, it is predicted to involve delivery of prepackaged effector proteins into the host cell that trigger plasma...

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Detalles Bibliográficos
Autores principales: Faris, Robert, McCullough, Alix, Andersen, Shelby E., Moninger, Thomas O., Weber, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526919/
https://www.ncbi.nlm.nih.gov/pubmed/32946535
http://dx.doi.org/10.1371/journal.ppat.1008878