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The role of α-ketoglutarate and the hypoxia sensing pathway in the regulation of pancreatic β-cell function
Anaplerosis and the associated mitochondrial metabolite transporters generate unique cytosolic metabolic signaling molecules that can regulate insulin release from pancreatic β-cells. It has been shown that mitochondrial metabolites, transported by the citrate carrier (CIC), dicarboxylate carrier (D...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527020/ https://www.ncbi.nlm.nih.gov/pubmed/32876527 http://dx.doi.org/10.1080/19382014.2020.1802183 |