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Herpes Simplex Virus 2 Counteracts Neurite Outgrowth Repulsion during Infection in a Nerve Growth Factor-Dependent Manner

During primary infection, herpes simplex virus 2 (HSV-2) replicates in epithelial cells and enters neurites to infect neurons of the peripheral nervous system. Growth factors and attractive and repulsive directional cues influence neurite outgrowth and neuronal survival. We hypothesized that HSV-2 m...

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Detalles Bibliográficos
Autores principales: Kropp, Kai A., López-Muñoz, Alberto Domingo, Ritter, Birgit, Martín, Rocío, Rastrojo, Alberto, Srivaratharajan, Sangar, Döhner, Katinka, Dhingra, Akshay, Czechowicz, Julia S., Nagel, Claus-Henning, Sodeik, Beate, Alcami, Antonio, Viejo-Borbolla, Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527038/
https://www.ncbi.nlm.nih.gov/pubmed/32669337
http://dx.doi.org/10.1128/JVI.01370-20