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Herpes Simplex Virus 2 Counteracts Neurite Outgrowth Repulsion during Infection in a Nerve Growth Factor-Dependent Manner
During primary infection, herpes simplex virus 2 (HSV-2) replicates in epithelial cells and enters neurites to infect neurons of the peripheral nervous system. Growth factors and attractive and repulsive directional cues influence neurite outgrowth and neuronal survival. We hypothesized that HSV-2 m...
Autores principales: | Kropp, Kai A., López-Muñoz, Alberto Domingo, Ritter, Birgit, Martín, Rocío, Rastrojo, Alberto, Srivaratharajan, Sangar, Döhner, Katinka, Dhingra, Akshay, Czechowicz, Julia S., Nagel, Claus-Henning, Sodeik, Beate, Alcami, Antonio, Viejo-Borbolla, Abel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527038/ https://www.ncbi.nlm.nih.gov/pubmed/32669337 http://dx.doi.org/10.1128/JVI.01370-20 |
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