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Structure of Merkel Cell Polyomavirus Capsid and Interaction with Its Glycosaminoglycan Attachment Receptor

Merkel cell polyomavirus (MCPyV) is a human double-stranded DNA tumor virus. MCPyV cell entry is unique among members of the polyomavirus family as it requires the engagement of two types of glycans, sialylated oligosaccharides and sulfated glycosaminoglycans (GAGs). Here, we present crystallographi...

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Detalles Bibliográficos
Autores principales: Bayer, Niklas J., Januliene, Dovile, Zocher, Georg, Stehle, Thilo, Moeller, Arne, Blaum, Bärbel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527053/
https://www.ncbi.nlm.nih.gov/pubmed/32699083
http://dx.doi.org/10.1128/JVI.01664-19

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