Serum citrullinated histone H3 concentrations differentiate patients with septic verses non-septic shock and correlate with disease severity

PURPOSE: Microbial infection stimulates neutrophil/macrophage/monocyte extracellular trap formation, which leads to the release of citrullinated histone H3 (CitH3) catalyzed by peptidylarginine deiminase (PAD) 2 and 4. Understanding these molecular mechanisms in the pathogenesis of septic shock will...

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Detalles Bibliográficos
Autores principales: Tian, Yuzi, Russo, Rachel M., Li, Yongqing, Karmakar, Monita, Liu, Baoling, Puskarich, Michael A., Jones, Alan E., Stringer, Kathleen A., Standiford, Theodore J., Alam, Hasan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527151/
https://www.ncbi.nlm.nih.gov/pubmed/33000445
http://dx.doi.org/10.1007/s15010-020-01528-y

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