Inhibition of two-pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4(+)Foxp3(+) regulatory T cells

CD4(+)Foxp3(+) regulatory T cells (T(regs)) are pivotal for the inhibition of autoimmune inflammatory responses. One way to therapeutically harness the immunosuppressive actions of T(regs) is to stimulate the proliferative expansion of TNFR2-expressing CD4(+)Foxp3(+) T(regs) via transmembrane TNF (t...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Tianzhen, Yang, De, Li, Xiao-Qing, Jiang, Mengmeng, Islam, Md Sahidul, Chen, Shaokui, Chen, Yibo, Yang, Yang, Chou, Chon-Kit, Trivett, Anna L., Oppenheim, Joost J., Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527222/
https://www.ncbi.nlm.nih.gov/pubmed/32998896
http://dx.doi.org/10.1126/sciadv.aba6584

Ejemplares similares

Ejemplares similares