Cargando…
An immune cocktail therapy to realize multiple boosting of the cancer-immunity cycle by combination of drug/gene delivery nanoparticles
Immune checkpoint blockade therapy (ICT) has shown potential in the treatment of multiple tumors, but suffers poor response rate in clinic. We found that even combining ICT with chemotherapy, which was wildly used in clinical trials, failed to achieve satisfactory tumor inhibition in the B16F10 mode...
Autores principales: | Wu, Jiayan, Chen, Jie, Feng, Yuanji, Zhang, Sijia, Lin, Lin, Guo, Zhaopei, Sun, Pingjie, Xu, Caina, Tian, Huayu, Chen, Xuesi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527226/ https://www.ncbi.nlm.nih.gov/pubmed/32998884 http://dx.doi.org/10.1126/sciadv.abc7828 |
Ejemplares similares
-
Production and clinical development of nanoparticles for gene delivery
por: Chen, Jie, et al.
Publicado: (2016) -
Combining mannose receptor mediated nanovaccines and gene regulated PD-L1 blockade for boosting cancer immunotherapy
por: Chen, Jie, et al.
Publicado: (2021) -
Combination of epigenetic regulation with gene therapy-mediated immune checkpoint blockade induces anti-tumour effects and immune response in vivo
por: Fang, Huapan, et al.
Publicado: (2021) -
Reactive oxygen species activated by mitochondria-specific camptothecin prodrug for enhanced chemotherapy
por: Guo, Zhaopei, et al.
Publicado: (2022) -
CD47KO/CRT dual-bioengineered cell membrane-coated nanovaccine combined with anti-PD-L1 antibody for boosting tumor immunotherapy
por: Liu, Shengyang, et al.
Publicado: (2022)