Probing single-cell metabolism reveals prognostic value of highly metabolically active circulating stromal cells in prostate cancer

Despite their important role in metastatic disease, no general method to detect circulating stromal cells (CStCs) exists. Here, we present the Metabolic Assay-Chip (MA-Chip) as a label-free, droplet-based microfluidic approach allowing single-cell extracellular pH measurement for the detection and i...

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Detalles Bibliográficos
Autores principales: Rivello, Francesca, Matuła, Kinga, Piruska, Aigars, Smits, Minke, Mehra, Niven, Huck, Wilhelm T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527228/
https://www.ncbi.nlm.nih.gov/pubmed/32998889
http://dx.doi.org/10.1126/sciadv.aaz3849

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