Neuroprotective effect of 3,3’-Diindolylmethane against perinatal asphyxia involves inhibition of the AhR and NMDA signaling and hypermethylation of specific genes

Each year, 1 million children die due to perinatal asphyxia; however, there are no effective drugs to protect the neonatal brain against hypoxic/ischemic damage. In this study, we demonstrated for the first time the neuroprotective capacity of 3,3’-diindolylmethane (DIM) in an in vivo model of rat p...

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Detalles Bibliográficos
Autores principales: Rzemieniec, J, Bratek, E, Wnuk, A, Przepiórska, K, Salińska, E, Kajta, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527327/
https://www.ncbi.nlm.nih.gov/pubmed/32816128
http://dx.doi.org/10.1007/s10495-020-01631-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527327/
https://www.ncbi.nlm.nih.gov/pubmed/32816128
http://dx.doi.org/10.1007/s10495-020-01631-3

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