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Topologically selective islet vulnerability and self-sustained downregulation of markers for β-cell maturity in streptozotocin-induced diabetes

Mouse models of Streptozotocin (STZ) induced diabetes represent the most widely used preclinical diabetes research systems. We applied state of the art optical imaging schemes, spanning from single islet resolution to the whole organ, providing a first longitudinal, 3D-spatial and quantitative accou...

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Detalles Bibliográficos
Autores principales:	Hahn, Max, van Krieken, Pim P., Nord, Christoffer, Alanentalo, Tomas, Morini, Federico, Xiong, Yan, Eriksson, Maria, Mayer, Jürgen, Kostromina, Elena, Ruas, Jorge L., Sharpe, James, Pereira, Teresa, Berggren, Per-Olof, Ilegems, Erwin, Ahlgren, Ulf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527346/ https://www.ncbi.nlm.nih.gov/pubmed/32999405 http://dx.doi.org/10.1038/s42003-020-01243-2

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