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Ancestral function of Inhibitors-of-kappaB regulates Caenorhabditis elegans development
Mammalian IκB proteins (IκBs) exert their main function as negative regulators of NF-κB, a central signaling pathway controlling immunity and inflammation. An alternative chromatin role for IκBs has been shown to affect stemness and cell differentiation. However, the involvement of NF-κB in this fun...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527347/ https://www.ncbi.nlm.nih.gov/pubmed/32999373 http://dx.doi.org/10.1038/s41598-020-73146-5 |