7-Hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation

We have developed a new and facile one pot three component protocol catalyzed by ammonium acetate for construction of new functionalized 7-hydroxy-4-phenyl-1,2-dihydroquinoline derivatives. A variety of quinoline derivatives were obtained in good to excellent yield from inexpensive reagents and cata...

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Detalles Bibliográficos
Autores principales: Tabassum, Rukhsana, Ashfaq, Muhammad, Oku, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527354/
https://www.ncbi.nlm.nih.gov/pubmed/33020745
http://dx.doi.org/10.1016/j.heliyon.2020.e05035
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author Tabassum, Rukhsana
Ashfaq, Muhammad
Oku, Hiroyuki
author_facet Tabassum, Rukhsana
Ashfaq, Muhammad
Oku, Hiroyuki
author_sort Tabassum, Rukhsana
collection PubMed
description We have developed a new and facile one pot three component protocol catalyzed by ammonium acetate for construction of new functionalized 7-hydroxy-4-phenyl-1,2-dihydroquinoline derivatives. A variety of quinoline derivatives were obtained in good to excellent yield from inexpensive reagents and catalyst in mild reaction conditions that provide atom economy and cost efficacy. Various spectroscopic techniques like FTIR, (1)HNMR and (13)CNMR were employed to study their structure while mass of the synthesized compounds were confirmed through MALDI-TOF-MS and EI mass spectrometry.
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spelling pubmed-75273542020-10-01 7-Hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation Tabassum, Rukhsana Ashfaq, Muhammad Oku, Hiroyuki Heliyon Research Article We have developed a new and facile one pot three component protocol catalyzed by ammonium acetate for construction of new functionalized 7-hydroxy-4-phenyl-1,2-dihydroquinoline derivatives. A variety of quinoline derivatives were obtained in good to excellent yield from inexpensive reagents and catalyst in mild reaction conditions that provide atom economy and cost efficacy. Various spectroscopic techniques like FTIR, (1)HNMR and (13)CNMR were employed to study their structure while mass of the synthesized compounds were confirmed through MALDI-TOF-MS and EI mass spectrometry. Elsevier 2020-10-01 /pmc/articles/PMC7527354/ /pubmed/33020745 http://dx.doi.org/10.1016/j.heliyon.2020.e05035 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Tabassum, Rukhsana
Ashfaq, Muhammad
Oku, Hiroyuki
7-Hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation
title 7-Hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation
title_full 7-Hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation
title_fullStr 7-Hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation
title_full_unstemmed 7-Hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation
title_short 7-Hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation
title_sort 7-hydroxy-4-phenyl-1, 2-dihydroquinoline derivatives: synthesis via one-pot, three-component reaction and structure elucidation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527354/
https://www.ncbi.nlm.nih.gov/pubmed/33020745
http://dx.doi.org/10.1016/j.heliyon.2020.e05035
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AT okuhiroyuki 7hydroxy4phenyl12dihydroquinolinederivativessynthesisviaonepotthreecomponentreactionandstructureelucidation

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