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Elevated IL-22 in psoriasis plays an anti-apoptotic role in keratinocytes through mediating Bcl-xL/Bax

IL-22 is known to mediate inflammation in psoriasis, while IL-22 binding protein (IL-22BP) binds IL-22 to suppress IL-22 signaling. However, the function of IL-22 in regulating apoptosis in psoriasis remains poorly understood. In this study, we found that IL-22/IL-22R1 in lesional skin and IL-22 in...

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Detalles Bibliográficos
Autores principales:	Wang, Bo, Han, Dan, Li, Fei, Hou, Weikun, Wang, Lijuan, Meng, Liesu, Mou, Kuanhou, Lu, Shemin, Zhu, Wenhua, Zhou, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527361/ https://www.ncbi.nlm.nih.gov/pubmed/32632545 http://dx.doi.org/10.1007/s10495-020-01623-3

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