In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase

Caloric restriction mimetics (CRMs) are promising molecules to prevent age-related diseases as they activate pathways driven by a true caloric restriction. Hydroxycitric acid (HCA) is considered a bona fide CRM since it depletes acetyl-CoA pools by acting as a competitive inhibitor of ATP citrate ly...

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Detalles Bibliográficos
Autores principales: Baroni, Maurizio D., Colombo, Sonia, Libens, Olivier, Pallavi, Rani, Giorgio, Marco, Martegani, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527365/
https://www.ncbi.nlm.nih.gov/pubmed/32666259
http://dx.doi.org/10.1007/s10495-020-01625-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527365/
https://www.ncbi.nlm.nih.gov/pubmed/32666259
http://dx.doi.org/10.1007/s10495-020-01625-1

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