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Synthesis and evaluation of N-isopropyl-p-[(11)C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography

INTRODUCTION: Increases in fasting plasma glucose (PG) levels lead to a decrease in 2-deoxy-2-[(18)F]fluoro-d-glucose ([(18)F]FDG) uptake in the normal brain, especially in the precuneus, resulting in an Alzheimer’s disease (AD)-like uptake pattern. Therefore, patients with higher PG levels, such as...

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Detalles Bibliográficos
Autores principales:	Toyohara, Jun, Harada, Norihiro, Kakiuchi, Takeharu, Ohba, Hiroyuki, Kanazawa, Masakatsu, Tago, Tetsuro, Sakata, Muneyuki, Ishiwata, Kiichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527401/ https://www.ncbi.nlm.nih.gov/pubmed/33000345 http://dx.doi.org/10.1186/s13550-020-00702-5

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