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Calibrating the Bacterial Growth Rate Speedometer: A Re-evaluation of the Relationship Between Basal ppGpp, Growth, and RNA Synthesis in Escherichia coli
The molecule guanosine tetraphophosphate (ppGpp) is most commonly considered an alarmone produced during acute stress. However, ppGpp is also present at low concentrations during steady-state growth. Whether ppGpp controls the same cellular targets at both low and high concentrations remains an open...
Autores principales: | Imholz, Nicole C. E., Noga, Marek J., van den Broek, Niels J. F., Bokinsky, Gregory |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527470/ https://www.ncbi.nlm.nih.gov/pubmed/33042085 http://dx.doi.org/10.3389/fmicb.2020.574872 |
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