Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis

Effectively activating macrophages against cancer is promising but challenging. In particular, cancer cells express CD47, a ‘don’t eat me’ signal that interacts with signal regulatory protein alpha (SIRPα) on macrophages to prevent phagocytosis. Also, cancer cells secrete stimulating factors, which...

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Detalles Bibliográficos
Autores principales: Rao, Lang, Wu, Lei, Liu, Zhida, Tian, Rui, Yu, Guocan, Zhou, Zijian, Yang, Kuikun, Xiong, Hong-Gang, Zhang, Anli, Yu, Guang-Tao, Sun, Wenjing, Xu, Han, Guo, Jingya, Li, Andrew, Chen, Hongmin, Sun, Zhi-Jun, Fu, Yang-Xin, Chen, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527506/
https://www.ncbi.nlm.nih.gov/pubmed/32999291
http://dx.doi.org/10.1038/s41467-020-18626-y

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