Cargando…

In situ Generated (212)Pb-PSMA Ligand in a (224)Ra-Solution for Dual Targeting of Prostate Cancer Sclerotic Stroma and PSMA-Positive Cells

Background: New treatments combating bone and extraskeletal metastases are needed for patients with metastatic castration-resistant prostate cancer. The majority of metastases overexpress prostate-specific membrane antigen (PSMA), making it an ideal candidate for targeted radionuclide therapy. Objec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stenberg, Vilde Y., Juzeniene, Asta, Bruland, Øyvind S., Larsen, Roy H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2020
Materias:	Pediatric
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527546/ https://www.ncbi.nlm.nih.gov/pubmed/32389119 http://dx.doi.org/10.2174/1874471013666200511000532

Ejemplares similares

Dual targeting with (224)Ra/(212)Pb-conjugates for targeted alpha therapy of disseminated cancers: A conceptual approach
por: Juzeniene, Asta, et al.
Publicado: (2023)

Evaluation of the PSMA-Binding Ligand (212)Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer
por: Stenberg, Vilde Yuli, et al.
Publicado: (2021)

Factors Influencing the Therapeutic Efficacy of the PSMA Targeting Radioligand (212)Pb-NG001
por: Stenberg, Vilde Yuli, et al.
Publicado: (2022)

Targeted alpha therapy with the (224)Ra/(212)Pb-TCMC-TP-3 dual alpha solution in a multicellular tumor spheroid model of osteosarcoma
por: Tornes, Anna Julie Kjøl, et al.
Publicado: (2022)

Preclinical and Clinical Status of PSMA-Targeted Alpha Therapy for Metastatic Castration-Resistant Prostate Cancer
por: Juzeniene, Asta, et al.
Publicado: (2021)

Development and dosimetry of (203)Pb/(212)Pb-labelled PSMA ligands: bringing “the lead” into PSMA-targeted alpha therapy?
por: dos Santos, José Carlos, et al.
Publicado: (2019)

Optimized SPECT Imaging of (224)Ra α-Particle Therapy by (212)Pb Photon Emissions
por: Mikalsen, Lars Tore Gyland, et al.
Publicado: (2023)

An Experimental Generator for Production of High-Purity (212)Pb for Use in Radiopharmaceuticals
por: Li, Ruth Gong, et al.
Publicado: (2023)

Therapeutic Effect of α-Emitting (224)Ra-Labeled Calcium Carbonate Microparticles in Mice with Intraperitoneal Ovarian Cancer()()
por: Westrøm, Sara, et al.
Publicado: (2018)

Improved Formulation of (224)Ra-Labeled Calcium Carbonate Microparticles by Surface Layer Encapsulation and Addition of EDTMP
por: Li, Ruth Gong, et al.
Publicado: (2021)

Ra‐224 labeling of calcium carbonate microparticles for internal α‐therapy: Preparation, stability, and biodistribution in mice
por: Westrøm, Sara, et al.
Publicado: (2018)

Radon-220 diffusion from (224)Ra-labeled calcium carbonate microparticles: Some implications for radiotherapeutic use
por: Napoli, Elisa, et al.
Publicado: (2021)

Imaging of (212)Pb in mice with a clinical SPECT/CT
por: Kvassheim, Monika, et al.
Publicado: (2023)

Should Low Molecular Weight PSMA Targeted Ligands Get Bigger and Use Albumin Ligands for PSMA Targeting?
por: Huang, Steve S., et al.
Publicado: (2017)

PSMA ligands for diagnosis and therapy of prostate cancer
por: Haberkorn, Uwe
Publicado: (2014)

Design of PSMA ligands with modifications at the inhibitor part: an approach to reduce the salivary gland uptake of radiolabeled PSMA inhibitors?
por: Felber, Veronika Barbara, et al.
Publicado: (2021)

Editorial: Targeted alpha particle therapy in oncology
por: Bruland, Øyvind Sverre, et al.
Publicado: (2023)

Search of ligands suitable for (212)Pb/(212)Bi in vivo generators
por: Bartoś, Barbara, et al.
Publicado: (2012)

The effect of eating on the uptake of PSMA ligands in the salivary glands
por: Mohan, V., et al.
Publicado: (2021)

Enzalutamide Enhances PSMA Expression of PSMA-Low Prostate Cancer
por: Staniszewska, Magdalena, et al.
Publicado: (2021)

(44)Sc-PSMA-617 for radiotheragnostics in tandem with (177)Lu-PSMA-617—preclinical investigations in comparison with (68)Ga-PSMA-11 and (68)Ga-PSMA-617
por: Umbricht, Christoph A., et al.
Publicado: (2017)

PSMA expression by microvasculature of thyroid tumors – Potential implications for PSMA theranostics
por: Bychkov, Andrey, et al.
Publicado: (2017)

GCP III is not the “off-target” for urea-based PSMA ligands
por: Lee, Zhenghong, et al.
Publicado: (2023)

Radiolabeled PSMA Inhibitors
por: Neels, Oliver C., et al.
Publicado: (2021)

Advances in PSMA theranostics
por: Jeitner, Thomas M., et al.
Publicado: (2022)

Heterogeneity of prostate-specific membrane antigen (PSMA) and PSMA-ligand uptake detection combining autoradiography and postoperative pathology in primary prostate cancer
por: Wang, Hui, et al.
Publicado: (2023)

PSMA Theranostics: Review of the Current Status of PSMA-Targeted Imaging and Radioligand Therapy
por: Jones, Wallace, et al.
Publicado: (2020)

All that Glitters on PSMA is Not a Lesion: An Unusual Artifact on PSMA PET/CT
por: Dev, Indraja D., et al.
Publicado: (2021)

Preclinical comparative study of [(18)F]AlF-PSMA-11 and [(18)F]PSMA-1007 in varying PSMA expressing tumors
por: Piron, Sarah, et al.
Publicado: (2022)

Multiparametric dynamic whole-body PSMA PET/CT using [(68)Ga]Ga-PSMA-11 and [(18)F]PSMA-1007
por: Dias, André H., et al.
Publicado: (2023)

A randomised, prospective and head-to-head comparison of [(68)Ga]Ga-PSMA-11 and [(18)F]PSMA-1007 for the detection of recurrent prostate cancer in PSMA-ligand PET/CT—Protocol design and rationale
por: Alberts, Ian, et al.
Publicado: (2022)

Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors
por: Ngen, Ethel J., et al.
Publicado: (2021)

Fine Structures in $^{14}C$ Emission of $^{223}Ra$ and $^{224}Ra$
por: Hourani, E, et al.
Publicado: (1991)

PSMA Ligands for Radionuclide Imaging and Therapy of Prostate Cancer: Clinical Status
por: Lütje, Susanne, et al.
Publicado: (2015)

PSMA Expression in Multinodular Thyroid Neoplasm on Simultaneous Ga-68-PSMA PET/MRI
por: Jena, Amarnath, et al.
Publicado: (2017)

E-PSMA: the EANM standardized reporting guidelines v1.0 for PSMA-PET
por: Ceci, Francesco, et al.
Publicado: (2021)

Deep learning and radiomics framework for PSMA-RADS classification of prostate cancer on PSMA PET
por: Leung, Kevin H., et al.
Publicado: (2022)

Octupole collectivity in $^{220}$Rn and $^{224}$Ra
por: Gaffney, Liam Paul
Publicado: (2013)

Probing two-alpha radioactivity with 224Ra
por: THEISEN, Christophe, et al.
Publicado: (2022)

Probing two-alpha radioactivity with 224Ra
por: Theisen, Christophe, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0g6m39vum61ga1j7oc70ao5278