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Longitudinal micro-computed tomography-derived biomarkers quantify non-resolving lung fibrosis in a silicosis mouse model
In spite of many compounds identified as antifibrotic in preclinical studies, pulmonary fibrosis remains a life-threatening condition for which highly effective treatment is still lacking. Towards improving the success-rate of bench-to-bedside translation, we investigated in vivo µCT-derived biomark...
Autores principales: | Dekoster, Kaat, Decaesteker, Tatjana, Berghen, Nathalie, Van den Broucke, Sofie, Jonckheere, Anne-Charlotte, Wouters, Jens, Krouglov, Anton, Lories, Rik, De Langhe, Ellen, Hoet, Peter, Verbeken, Erik, Vanoirbeek, Jeroen, Vande Velde, Greetje |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527558/ https://www.ncbi.nlm.nih.gov/pubmed/32999350 http://dx.doi.org/10.1038/s41598-020-73056-6 |
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