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Malaria among febrile neonates attending the neonatology unit of the Bamenda regional hospital
Malaria remains the leading cause of infant’s mortality in malaria endemic countries like Cameroon. Due to the presence of passively acquired maternal antibodies, malaria in neonates was thought to be scarce. Consequently routine malaria checks are mostly not considered for febrile neonates. Nonethe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527715/ https://www.ncbi.nlm.nih.gov/pubmed/33024846 http://dx.doi.org/10.1016/j.parepi.2020.e00184 |
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author | Nfor, Nlinwe Omarine Senyuy, Dzewong Thierry |
author_facet | Nfor, Nlinwe Omarine Senyuy, Dzewong Thierry |
author_sort | Nfor, Nlinwe Omarine |
collection | PubMed |
description | Malaria remains the leading cause of infant’s mortality in malaria endemic countries like Cameroon. Due to the presence of passively acquired maternal antibodies, malaria in neonates was thought to be scarce. Consequently routine malaria checks are mostly not considered for febrile neonates. Nonetheless findings from malaria endemic areas have proven that malaria in neonates is not uncommon. This study is therefore designed to evaluate malaria among febrile neonates attending the neonatology unit of the Bamenda Regional Hospital. A structured questionnaire and laboratory diagnostic test methods were used for data collection. Maternal sociodemographic data and malaria predisposing factors for neonates with and without malaria were determined using sums and percentages of mean. Regression analysis was used to determine the effects of age of mother, parity, mother’s educational level, sex of neonate and malaria predisposing factors on malaria parasitaemia. Chi-square (and Fisher’s exact) test was used to calculate sensitivity (%), specificity (%), predictive values (%), likelihood ratios, odd ratios, relative risk and attributable risk. A total of 189 neonates were included in the study out of which 33 (17.46%) tested malaria positive. 54.55% (18/33) of the malaria positive neonates were˃ 3 – 4 weeks old, while only 09.09% (03/33) were within 0 – 1 week of age. Neonates who presented with both signs of “fever + refusal to feed” were found to be most likely (P = 0.0188) to test malaria positive. Based on these findings routine malaria test is recommended especially for all neonates who presents with both signs of “fever + refusal to feed”, in malaria endemic regions. |
format | Online Article Text |
id | pubmed-7527715 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-75277152020-10-05 Malaria among febrile neonates attending the neonatology unit of the Bamenda regional hospital Nfor, Nlinwe Omarine Senyuy, Dzewong Thierry Parasite Epidemiol Control Original Research article Malaria remains the leading cause of infant’s mortality in malaria endemic countries like Cameroon. Due to the presence of passively acquired maternal antibodies, malaria in neonates was thought to be scarce. Consequently routine malaria checks are mostly not considered for febrile neonates. Nonetheless findings from malaria endemic areas have proven that malaria in neonates is not uncommon. This study is therefore designed to evaluate malaria among febrile neonates attending the neonatology unit of the Bamenda Regional Hospital. A structured questionnaire and laboratory diagnostic test methods were used for data collection. Maternal sociodemographic data and malaria predisposing factors for neonates with and without malaria were determined using sums and percentages of mean. Regression analysis was used to determine the effects of age of mother, parity, mother’s educational level, sex of neonate and malaria predisposing factors on malaria parasitaemia. Chi-square (and Fisher’s exact) test was used to calculate sensitivity (%), specificity (%), predictive values (%), likelihood ratios, odd ratios, relative risk and attributable risk. A total of 189 neonates were included in the study out of which 33 (17.46%) tested malaria positive. 54.55% (18/33) of the malaria positive neonates were˃ 3 – 4 weeks old, while only 09.09% (03/33) were within 0 – 1 week of age. Neonates who presented with both signs of “fever + refusal to feed” were found to be most likely (P = 0.0188) to test malaria positive. Based on these findings routine malaria test is recommended especially for all neonates who presents with both signs of “fever + refusal to feed”, in malaria endemic regions. Elsevier 2020-09-25 /pmc/articles/PMC7527715/ /pubmed/33024846 http://dx.doi.org/10.1016/j.parepi.2020.e00184 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Research article Nfor, Nlinwe Omarine Senyuy, Dzewong Thierry Malaria among febrile neonates attending the neonatology unit of the Bamenda regional hospital |
title | Malaria among febrile neonates attending the neonatology unit of the Bamenda regional hospital |
title_full | Malaria among febrile neonates attending the neonatology unit of the Bamenda regional hospital |
title_fullStr | Malaria among febrile neonates attending the neonatology unit of the Bamenda regional hospital |
title_full_unstemmed | Malaria among febrile neonates attending the neonatology unit of the Bamenda regional hospital |
title_short | Malaria among febrile neonates attending the neonatology unit of the Bamenda regional hospital |
title_sort | malaria among febrile neonates attending the neonatology unit of the bamenda regional hospital |
topic | Original Research article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527715/ https://www.ncbi.nlm.nih.gov/pubmed/33024846 http://dx.doi.org/10.1016/j.parepi.2020.e00184 |
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