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Human Cytomegalovirus Genomes Survive Mitosis via the IE19 Chromatin-Tethering Domain

The genomes of DNA tumor viruses regain nuclear localization after nuclear envelope breakdown during mitosis through the action of a viral protein with a chromatin-tethering domain (CTD). Here, we report that the human cytomegalovirus (HCMV) genome is maintained during mitosis by the CTD of the vira...

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Detalles Bibliográficos
Autores principales: Lyon, Shelby M., Yetming, Kristen D., Paulus, Christina, Nevels, Michael, Kalejta, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527735/
https://www.ncbi.nlm.nih.gov/pubmed/32994332
http://dx.doi.org/10.1128/mBio.02410-20

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