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Development of an Improved 3D in vitro Intestinal Model to Perform Permeability Studies of Paracellular Compounds

The small intestine is the primary site of drug absorption following oral administration, making paramount the proper monitoring of the absorption process. In vitro tools to predict intestinal absorption are particularly important in preclinical drug development since they are less laborious and cos...

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Detalles Bibliográficos
Autores principales: Macedo, Maria Helena, Martínez, Elena, Barrias, Cristina C., Sarmento, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527803/
https://www.ncbi.nlm.nih.gov/pubmed/33042961
http://dx.doi.org/10.3389/fbioe.2020.524018