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Development of an Improved 3D in vitro Intestinal Model to Perform Permeability Studies of Paracellular Compounds
The small intestine is the primary site of drug absorption following oral administration, making paramount the proper monitoring of the absorption process. In vitro tools to predict intestinal absorption are particularly important in preclinical drug development since they are less laborious and cos...
Autores principales: | Macedo, Maria Helena, Martínez, Elena, Barrias, Cristina C., Sarmento, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527803/ https://www.ncbi.nlm.nih.gov/pubmed/33042961 http://dx.doi.org/10.3389/fbioe.2020.524018 |
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