Proteasomal degradation induced by DPP9‐mediated processing competes with mitochondrial protein import

Plasticity of the proteome is critical to adapt to varying conditions. Control of mitochondrial protein import contributes to this plasticity. Here, we identified a pathway that regulates mitochondrial protein import by regulated N‐terminal processing. We demonstrate that dipeptidyl peptidases 8/9 (...

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Detalles Bibliográficos
Autores principales: Finger, Yannik, Habich, Markus, Gerlich, Sarah, Urbanczyk, Sophia, van de Logt, Erik, Koch, Julian, Schu, Laura, Lapacz, Kim Jasmin, Ali, Muna, Petrungaro, Carmelina, Salscheider, Silja Lucia, Pichlo, Christian, Baumann, Ulrich, Mielenz, Dirk, Dengjel, Joern, Brachvogel, Bent, Hofmann, Kay, Riemer, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527813/
https://www.ncbi.nlm.nih.gov/pubmed/32815200
http://dx.doi.org/10.15252/embj.2019103889

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