CARD8 inflammasome activation triggers pyroptosis in human T cells

Inflammasomes execute a unique type of cell death known as pyroptosis. Mostly characterized in myeloid cells, caspase‐1 activation downstream of an inflammasome sensor results in the cleavage and activation of gasdermin D (GSDMD), which then forms a lytic pore in the plasma membrane. Recently, CARD8...

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Detalles Bibliográficos
Autores principales: Linder, Andreas, Bauernfried, Stefan, Cheng, Yiming, Albanese, Manuel, Jung, Christophe, Keppler, Oliver T, Hornung, Veit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527815/
https://www.ncbi.nlm.nih.gov/pubmed/32840892
http://dx.doi.org/10.15252/embj.2020105071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527815/
https://www.ncbi.nlm.nih.gov/pubmed/32840892
http://dx.doi.org/10.15252/embj.2020105071

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