Cargando…

Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study

OBJECTIVES: To determine the rate of complicated birth at term in women classified at low risk according to the National Institute for Health and Care Excellence guideline for intrapartum care (no pre-existing medical conditions, important obstetric history, or complications during pregnancy) and to...

Descripción completa

Detalles Bibliográficos
Autores principales: Jardine, Jennifer, Blotkamp, Andrea, Gurol-Urganci, Ipek, Knight, Hannah, Harris, Tina, Hawdon, Jane, van der Meulen, Jan, Walker, Kate, Pasupathy, Dharmintra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527835/
https://www.ncbi.nlm.nih.gov/pubmed/33004347
http://dx.doi.org/10.1136/bmj.m3377
_version_ 1783589142707306496
author Jardine, Jennifer
Blotkamp, Andrea
Gurol-Urganci, Ipek
Knight, Hannah
Harris, Tina
Hawdon, Jane
van der Meulen, Jan
Walker, Kate
Pasupathy, Dharmintra
author_facet Jardine, Jennifer
Blotkamp, Andrea
Gurol-Urganci, Ipek
Knight, Hannah
Harris, Tina
Hawdon, Jane
van der Meulen, Jan
Walker, Kate
Pasupathy, Dharmintra
author_sort Jardine, Jennifer
collection PubMed
description OBJECTIVES: To determine the rate of complicated birth at term in women classified at low risk according to the National Institute for Health and Care Excellence guideline for intrapartum care (no pre-existing medical conditions, important obstetric history, or complications during pregnancy) and to assess if the risk classification can be improved by considering parity and the number of risk factors. DESIGN: Cohort study using linked electronic maternity records. PARTICIPANTS: 276 766 women with a singleton birth at term after a trial of labour in 87 NHS hospital trusts in England between April 2015 and March 2016. MAIN OUTCOME MEASURE: A composite outcome of complicated birth, defined as a birth with use of an instrument, caesarean delivery, anal sphincter injury, postpartum haemorrhage, or Apgar score of 7 or less at five minutes. RESULTS: Multiparous women without a history of caesarean section had the lowest rates of complicated birth, varying from 8.8% (4879 of 55 426 women, 95% confidence interval 8.6% to 9.0%) in those without specific risk factors to 21.8% (613 of 2811 women, 20.2% to 23.4%) in those with three or more. The rate of complicated birth was higher in nulliparous women, with corresponding rates varying from 43.4% (25  805 of 59 413 women, 43.0% to 43.8%) to 64.3% (364 of 566 women, 60.3% to 68.3%); and highest in multiparous women with previous caesarean section, with corresponding rates varying from 42.9% (3426 of 7993 women, 41.8% to 44.0%) to 66.3% (554 of 836 women, 63.0% to 69.5%). CONCLUSIONS: Nulliparous women without risk factors have substantially higher rates of complicated birth than multiparous women without a previous caesarean section even if the latter have multiple risk factors. Grouping women first according to parity and previous mode of birth, and then within these groups according to presence of specific risk factors would provide greater and more informed choice to women, better targeting of interventions, and fewer transfers during labour than according to the presence of risk factors alone.
format Online
Article
Text
id pubmed-7527835
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BMJ Publishing Group Ltd.
record_format MEDLINE/PubMed
spelling pubmed-75278352020-10-19 Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study Jardine, Jennifer Blotkamp, Andrea Gurol-Urganci, Ipek Knight, Hannah Harris, Tina Hawdon, Jane van der Meulen, Jan Walker, Kate Pasupathy, Dharmintra BMJ Research OBJECTIVES: To determine the rate of complicated birth at term in women classified at low risk according to the National Institute for Health and Care Excellence guideline for intrapartum care (no pre-existing medical conditions, important obstetric history, or complications during pregnancy) and to assess if the risk classification can be improved by considering parity and the number of risk factors. DESIGN: Cohort study using linked electronic maternity records. PARTICIPANTS: 276 766 women with a singleton birth at term after a trial of labour in 87 NHS hospital trusts in England between April 2015 and March 2016. MAIN OUTCOME MEASURE: A composite outcome of complicated birth, defined as a birth with use of an instrument, caesarean delivery, anal sphincter injury, postpartum haemorrhage, or Apgar score of 7 or less at five minutes. RESULTS: Multiparous women without a history of caesarean section had the lowest rates of complicated birth, varying from 8.8% (4879 of 55 426 women, 95% confidence interval 8.6% to 9.0%) in those without specific risk factors to 21.8% (613 of 2811 women, 20.2% to 23.4%) in those with three or more. The rate of complicated birth was higher in nulliparous women, with corresponding rates varying from 43.4% (25  805 of 59 413 women, 43.0% to 43.8%) to 64.3% (364 of 566 women, 60.3% to 68.3%); and highest in multiparous women with previous caesarean section, with corresponding rates varying from 42.9% (3426 of 7993 women, 41.8% to 44.0%) to 66.3% (554 of 836 women, 63.0% to 69.5%). CONCLUSIONS: Nulliparous women without risk factors have substantially higher rates of complicated birth than multiparous women without a previous caesarean section even if the latter have multiple risk factors. Grouping women first according to parity and previous mode of birth, and then within these groups according to presence of specific risk factors would provide greater and more informed choice to women, better targeting of interventions, and fewer transfers during labour than according to the presence of risk factors alone. BMJ Publishing Group Ltd. 2020-10-01 /pmc/articles/PMC7527835/ /pubmed/33004347 http://dx.doi.org/10.1136/bmj.m3377 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Research
Jardine, Jennifer
Blotkamp, Andrea
Gurol-Urganci, Ipek
Knight, Hannah
Harris, Tina
Hawdon, Jane
van der Meulen, Jan
Walker, Kate
Pasupathy, Dharmintra
Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study
title Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study
title_full Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study
title_fullStr Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study
title_full_unstemmed Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study
title_short Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study
title_sort risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in england: cohort study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527835/
https://www.ncbi.nlm.nih.gov/pubmed/33004347
http://dx.doi.org/10.1136/bmj.m3377
work_keys_str_mv AT jardinejennifer riskofcomplicatedbirthatterminnulliparousandmultiparouswomenusingroutinelycollectedmaternitydatainenglandcohortstudy
AT blotkampandrea riskofcomplicatedbirthatterminnulliparousandmultiparouswomenusingroutinelycollectedmaternitydatainenglandcohortstudy
AT gurolurganciipek riskofcomplicatedbirthatterminnulliparousandmultiparouswomenusingroutinelycollectedmaternitydatainenglandcohortstudy
AT knighthannah riskofcomplicatedbirthatterminnulliparousandmultiparouswomenusingroutinelycollectedmaternitydatainenglandcohortstudy
AT harristina riskofcomplicatedbirthatterminnulliparousandmultiparouswomenusingroutinelycollectedmaternitydatainenglandcohortstudy
AT hawdonjane riskofcomplicatedbirthatterminnulliparousandmultiparouswomenusingroutinelycollectedmaternitydatainenglandcohortstudy
AT vandermeulenjan riskofcomplicatedbirthatterminnulliparousandmultiparouswomenusingroutinelycollectedmaternitydatainenglandcohortstudy
AT walkerkate riskofcomplicatedbirthatterminnulliparousandmultiparouswomenusingroutinelycollectedmaternitydatainenglandcohortstudy
AT pasupathydharmintra riskofcomplicatedbirthatterminnulliparousandmultiparouswomenusingroutinelycollectedmaternitydatainenglandcohortstudy