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Nox4 regulates InsP(3) receptor‐dependent Ca(2+) release into mitochondria to promote cell survival
Cells subjected to environmental stresses undergo regulated cell death (RCD) when homeostatic programs fail to maintain viability. A major mechanism of RCD is the excessive calcium loading of mitochondria and consequent triggering of the mitochondrial permeability transition (mPT), which is especial...
Autores principales: | Beretta, Matteo, Santos, Celio XC, Molenaar, Chris, Hafstad, Anne D, Miller, Chris CJ, Revazian, Aram, Betteridge, Kai, Schröder, Katrin, Streckfuß‐Bömeke, Katrin, Doroshow, James H, Fleck, Roland A, Su, Tsung‐Ping, Belousov, Vsevolod V, Parsons, Maddy, Shah, Ajay M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527947/ https://www.ncbi.nlm.nih.gov/pubmed/33001475 http://dx.doi.org/10.15252/embj.2019103530 |
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