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Next-generation sequencing in the diagnosis of viral encephalitis: sensitivity and clinical limitations

Identification of pathogens causing viral encephalitis remains challenging, and in over 50% of cases the etiologic factor remains undetermined. Next-generation sequencing (NGS) based metagenomics has been successfully used to detect novel and rare infections, but its value for routine diagnosis of e...

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Detalles Bibliográficos
Autores principales: Perlejewski, Karol, Bukowska-Ośko, Iwona, Rydzanicz, Małgorzata, Pawełczyk, Agnieszka, Caraballo Cortѐs, Kamila, Osuch, Sylwia, Paciorek, Marcin, Dzieciątkowski, Tomasz, Radkowski, Marek, Laskus, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528011/
https://www.ncbi.nlm.nih.gov/pubmed/32999423
http://dx.doi.org/10.1038/s41598-020-73156-3