Oxygen glucose deprivation/re-oxygenation-induced neuronal cell death is associated with Lnc-D63785 m6A methylation and miR-422a accumulation

Oxygen glucose deprivation/re-oxygenation (OGD/R) induces neuronal injury via mechanisms that are believed to mimic the pathways associated with brain ischemia. In SH-SY5Y cells and primary murine neurons, we report that OGD/R induces the accumulation of the microRNA miR-422a, leading to downregulat...

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Detalles Bibliográficos
Autores principales: Xu, Shu, Li, Ya, Chen, Ju-ping, Li, Da-Zhuang, Jiang, Qin, Wu, Ting, Zhou, Xiao-zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528015/
https://www.ncbi.nlm.nih.gov/pubmed/32999283
http://dx.doi.org/10.1038/s41419-020-03021-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528015/
https://www.ncbi.nlm.nih.gov/pubmed/32999283
http://dx.doi.org/10.1038/s41419-020-03021-8

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