Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets

To elucidate the molecular pathogenesis of pediatric germ cell tumors (GCTs), we performed DNA methylation array analysis, whole transcriptome sequencing, targeted capture sequencing, and single-nucleotide polymorphism array analysis using 51 GCT samples (25 female, 26 male), including 6 germinomas,...

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Detalles Bibliográficos
Autores principales: Kubota, Yasuo, Seki, Masafumi, Kawai, Tomoko, Isobe, Tomoya, Yoshida, Misa, Sekiguchi, Masahiro, Kimura, Shunsuke, Watanabe, Kentaro, Sato-Otsubo, Aiko, Yoshida, Kenichi, Suzuki, Hiromichi, Kataoka, Keisuke, Fujii, Yoichi, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Hiwatari, Mitsuteru, Oka, Akira, Hayashi, Yasuhide, Miyano, Satoru, Ogawa, Seishi, Hata, Kenichiro, Tanaka, Yukichi, Takita, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528104/
https://www.ncbi.nlm.nih.gov/pubmed/32999426
http://dx.doi.org/10.1038/s42003-020-01267-8

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