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Predisposition of Neonatal Maternal Separation to Visceral Hypersensitivity via Downregulation of Small-Conductance Calcium-Activated Potassium Channel Subtype 2 (SK2) in Mice
BACKGROUND: Visceral hypersensitivity is a common occurrence of gastrointestinal diseases such as irritable bowel syndrome (IBS), wherein early-life stress (ELS) may have a high predisposition to the development of visceral hypersensitivity in adulthood, with the specific underlying mechanism still...
Autores principales: | Wu, Ke, Gao, Jing-hua, Hua, Rong, Peng, Xiao-han, Wang, Hui, Zhang, Yong-mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528131/ https://www.ncbi.nlm.nih.gov/pubmed/33029124 http://dx.doi.org/10.1155/2020/8876230 |
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