Development and Validation of an LC–MS-Based Quantification Assay for New Therapeutic Antibodies: Application to a Novel Therapy against Herpes Simplex Virus

[Image: see text] Multiple therapeutic monoclonal antibodies (mAbs) are currently under development or in (pre)clinical study phases to reach regulatory approval. Among these, a new mAb against herpes simplex virus, HDIT101, was recently tested in healthy volunteers during a phase I clinical trial (...

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Detalles Bibliográficos
Autores principales: Fresnais, Margaux, Longuespée, Rémi, Sauter, Max, Schaller, Torsten, Arndt, Michaela, Krauss, Jürgen, Blank, Antje, Haefeli, Walter E., Burhenne, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528202/
https://www.ncbi.nlm.nih.gov/pubmed/33015449
http://dx.doi.org/10.1021/acsomega.0c02547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528202/
https://www.ncbi.nlm.nih.gov/pubmed/33015449
http://dx.doi.org/10.1021/acsomega.0c02547

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