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Oral administration of NPC43 counters hyperglycemia and activates insulin receptor in streptozotocin-induced type 1 diabetic mice

INTRODUCTION: Adenosine, 5’-Se-methyl-5’-seleno-,2’,3’-diacetate (NPC43) is a recently identified small, non-peptidyl molecule which restores normal insulin signaling in a mouse model of type 2 diabetes (Lan et al). The present study investigated the ability of NPC43 as an oral and injectable insuli...

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Detalles Bibliográficos
Autores principales:	Lan, Zi-Jian, Lei, Zhenmin, Nation, Lucinda, Li, Xian, Yiannikouris, Alexandros, Yerramreddy, Thirupathi Reddy, Kincaid, Hayley, Eastridge, Katie, Xiao, Rijin, Goettl, Ryan, Power, Ronan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Emerging Technologies, Pharmacology and Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528369/ https://www.ncbi.nlm.nih.gov/pubmed/32998869 http://dx.doi.org/10.1136/bmjdrc-2020-001695

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