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Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation
We present Mustache, a new method for multi-scale detection of chromatin loops from Hi-C and Micro-C contact maps. Mustache employs scale-space theory, a technical advance in computer vision, to detect blob-shaped objects in contact maps. Mustache is scalable to kilobase-resolution maps and reports...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528378/ https://www.ncbi.nlm.nih.gov/pubmed/32998764 http://dx.doi.org/10.1186/s13059-020-02167-0 |