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Targeted next-generation sequencing assays using triplet samples of normal breast tissue, primary breast cancer, and recurrent/metastatic lesions
BACKGROUND: Next-generation sequencing (NGS) has shown that recurrent/metastatic breast cancer lesions may have additional genetic changes compared with the primary tumor. These additional changes may be related to tumor progression and/or drug resistance. However, breast cancer-targeted NGS is not...
Autores principales: | Akahane, Toshiaki, Kanomata, Naoki, Harada, Oi, Yamashita, Tetsumasa, Kurebayashi, Junichi, Tanimoto, Akihide, Moriya, Takuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528467/ https://www.ncbi.nlm.nih.gov/pubmed/33004031 http://dx.doi.org/10.1186/s12885-020-07432-w |
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