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Molecular contribution of BRCA1 and BRCA2 to genome instability in breast cancer patients: review of radiosensitivity assays

BACKGROUND: DNA repair pathways, cell cycle arrest checkpoints, and cell death induction are present in cells to process DNA damage and prevent genomic instability caused by various extrinsic and intrinsic ionizing factors. Mutations in the genes involved in these pathways enhances the ionizing radi...

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Detalles Bibliográficos
Autores principales:	Sadeghi, Fatemeh, Asgari, Marzieh, Matloubi, Mojdeh, Ranjbar, Maral, Karkhaneh Yousefi, Nahid, Azari, Tahereh, Zaki-Dizaji, Majid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528506/ https://www.ncbi.nlm.nih.gov/pubmed/33013205 http://dx.doi.org/10.1186/s12575-020-00133-5

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