Cargando…

Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites

There is a lack of focus on the protective health effects of phytochemicals in dietary guidelines. Although a number of chemical libraries and databases contain dietary phytochemicals belonging to the plant metabolome, they are not entirely relevant to human health because many constituents are exte...

Descripción completa

Detalles Bibliográficos
Autores principales: Kay, Colin D, Clifford, Michael N, Mena, Pedro, McDougall, Gordon J, Andres-Lacueva, Cristina, Cassidy, Aedin, Del Rio, Daniele, Kuhnert, Nikolai, Manach, Claudine, Pereira-Caro, Gema, Rodriguez-Mateos, Ana, Scalbert, Augustin, Tomás-Barberán, Francisco, Williamson, Gary, Wishart, David S, Crozier, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528558/
https://www.ncbi.nlm.nih.gov/pubmed/32936878
http://dx.doi.org/10.1093/ajcn/nqaa204
_version_ 1783589286283575296
author Kay, Colin D
Clifford, Michael N
Mena, Pedro
McDougall, Gordon J
Andres-Lacueva, Cristina
Cassidy, Aedin
Del Rio, Daniele
Kuhnert, Nikolai
Manach, Claudine
Pereira-Caro, Gema
Rodriguez-Mateos, Ana
Scalbert, Augustin
Tomás-Barberán, Francisco
Williamson, Gary
Wishart, David S
Crozier, Alan
author_facet Kay, Colin D
Clifford, Michael N
Mena, Pedro
McDougall, Gordon J
Andres-Lacueva, Cristina
Cassidy, Aedin
Del Rio, Daniele
Kuhnert, Nikolai
Manach, Claudine
Pereira-Caro, Gema
Rodriguez-Mateos, Ana
Scalbert, Augustin
Tomás-Barberán, Francisco
Williamson, Gary
Wishart, David S
Crozier, Alan
author_sort Kay, Colin D
collection PubMed
description There is a lack of focus on the protective health effects of phytochemicals in dietary guidelines. Although a number of chemical libraries and databases contain dietary phytochemicals belonging to the plant metabolome, they are not entirely relevant to human health because many constituents are extensively metabolized within the body following ingestion. This is especially apparent for the highly abundant dietary (poly)phenols, for which the situation is compounded by confusion regarding their bioavailability and metabolism, partially because of the variety of nomenclatures and trivial names used to describe compounds arising from microbial catabolism in the gastrointestinal tract. This confusion, which is perpetuated in online chemical/metabolite databases, will hinder future discovery of bioactivities and affect the establishment of future dietary guidelines if steps are not taken to overcome these issues. In order to resolve this situation, a nomenclature system for phenolic catabolites and their human phase II metabolites is proposed in this article and the basis of its format outlined. Previous names used in the literature are cited along with the recommended nomenclature, International Union of Pure and Applied Chemistry terminology, and, where appropriate, Chemical Abstracts Service numbers, InChIKey, and accurate mass.
format Online
Article
Text
id pubmed-7528558
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-75285582020-10-07 Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites Kay, Colin D Clifford, Michael N Mena, Pedro McDougall, Gordon J Andres-Lacueva, Cristina Cassidy, Aedin Del Rio, Daniele Kuhnert, Nikolai Manach, Claudine Pereira-Caro, Gema Rodriguez-Mateos, Ana Scalbert, Augustin Tomás-Barberán, Francisco Williamson, Gary Wishart, David S Crozier, Alan Am J Clin Nutr Special Article There is a lack of focus on the protective health effects of phytochemicals in dietary guidelines. Although a number of chemical libraries and databases contain dietary phytochemicals belonging to the plant metabolome, they are not entirely relevant to human health because many constituents are extensively metabolized within the body following ingestion. This is especially apparent for the highly abundant dietary (poly)phenols, for which the situation is compounded by confusion regarding their bioavailability and metabolism, partially because of the variety of nomenclatures and trivial names used to describe compounds arising from microbial catabolism in the gastrointestinal tract. This confusion, which is perpetuated in online chemical/metabolite databases, will hinder future discovery of bioactivities and affect the establishment of future dietary guidelines if steps are not taken to overcome these issues. In order to resolve this situation, a nomenclature system for phenolic catabolites and their human phase II metabolites is proposed in this article and the basis of its format outlined. Previous names used in the literature are cited along with the recommended nomenclature, International Union of Pure and Applied Chemistry terminology, and, where appropriate, Chemical Abstracts Service numbers, InChIKey, and accurate mass. Oxford University Press 2020-09-16 /pmc/articles/PMC7528558/ /pubmed/32936878 http://dx.doi.org/10.1093/ajcn/nqaa204 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the American Society for Nutrition. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Article
Kay, Colin D
Clifford, Michael N
Mena, Pedro
McDougall, Gordon J
Andres-Lacueva, Cristina
Cassidy, Aedin
Del Rio, Daniele
Kuhnert, Nikolai
Manach, Claudine
Pereira-Caro, Gema
Rodriguez-Mateos, Ana
Scalbert, Augustin
Tomás-Barberán, Francisco
Williamson, Gary
Wishart, David S
Crozier, Alan
Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites
title Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites
title_full Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites
title_fullStr Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites
title_full_unstemmed Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites
title_short Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites
title_sort recommendations for standardizing nomenclature for dietary (poly)phenol catabolites
topic Special Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528558/
https://www.ncbi.nlm.nih.gov/pubmed/32936878
http://dx.doi.org/10.1093/ajcn/nqaa204
work_keys_str_mv AT kaycolind recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT cliffordmichaeln recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT menapedro recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT mcdougallgordonj recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT andreslacuevacristina recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT cassidyaedin recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT delriodaniele recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT kuhnertnikolai recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT manachclaudine recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT pereiracarogema recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT rodriguezmateosana recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT scalbertaugustin recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT tomasbarberanfrancisco recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT williamsongary recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT wishartdavids recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites
AT crozieralan recommendationsforstandardizingnomenclaturefordietarypolyphenolcatabolites