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Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites
There is a lack of focus on the protective health effects of phytochemicals in dietary guidelines. Although a number of chemical libraries and databases contain dietary phytochemicals belonging to the plant metabolome, they are not entirely relevant to human health because many constituents are exte...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528558/ https://www.ncbi.nlm.nih.gov/pubmed/32936878 http://dx.doi.org/10.1093/ajcn/nqaa204 |
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author | Kay, Colin D Clifford, Michael N Mena, Pedro McDougall, Gordon J Andres-Lacueva, Cristina Cassidy, Aedin Del Rio, Daniele Kuhnert, Nikolai Manach, Claudine Pereira-Caro, Gema Rodriguez-Mateos, Ana Scalbert, Augustin Tomás-Barberán, Francisco Williamson, Gary Wishart, David S Crozier, Alan |
author_facet | Kay, Colin D Clifford, Michael N Mena, Pedro McDougall, Gordon J Andres-Lacueva, Cristina Cassidy, Aedin Del Rio, Daniele Kuhnert, Nikolai Manach, Claudine Pereira-Caro, Gema Rodriguez-Mateos, Ana Scalbert, Augustin Tomás-Barberán, Francisco Williamson, Gary Wishart, David S Crozier, Alan |
author_sort | Kay, Colin D |
collection | PubMed |
description | There is a lack of focus on the protective health effects of phytochemicals in dietary guidelines. Although a number of chemical libraries and databases contain dietary phytochemicals belonging to the plant metabolome, they are not entirely relevant to human health because many constituents are extensively metabolized within the body following ingestion. This is especially apparent for the highly abundant dietary (poly)phenols, for which the situation is compounded by confusion regarding their bioavailability and metabolism, partially because of the variety of nomenclatures and trivial names used to describe compounds arising from microbial catabolism in the gastrointestinal tract. This confusion, which is perpetuated in online chemical/metabolite databases, will hinder future discovery of bioactivities and affect the establishment of future dietary guidelines if steps are not taken to overcome these issues. In order to resolve this situation, a nomenclature system for phenolic catabolites and their human phase II metabolites is proposed in this article and the basis of its format outlined. Previous names used in the literature are cited along with the recommended nomenclature, International Union of Pure and Applied Chemistry terminology, and, where appropriate, Chemical Abstracts Service numbers, InChIKey, and accurate mass. |
format | Online Article Text |
id | pubmed-7528558 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-75285582020-10-07 Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites Kay, Colin D Clifford, Michael N Mena, Pedro McDougall, Gordon J Andres-Lacueva, Cristina Cassidy, Aedin Del Rio, Daniele Kuhnert, Nikolai Manach, Claudine Pereira-Caro, Gema Rodriguez-Mateos, Ana Scalbert, Augustin Tomás-Barberán, Francisco Williamson, Gary Wishart, David S Crozier, Alan Am J Clin Nutr Special Article There is a lack of focus on the protective health effects of phytochemicals in dietary guidelines. Although a number of chemical libraries and databases contain dietary phytochemicals belonging to the plant metabolome, they are not entirely relevant to human health because many constituents are extensively metabolized within the body following ingestion. This is especially apparent for the highly abundant dietary (poly)phenols, for which the situation is compounded by confusion regarding their bioavailability and metabolism, partially because of the variety of nomenclatures and trivial names used to describe compounds arising from microbial catabolism in the gastrointestinal tract. This confusion, which is perpetuated in online chemical/metabolite databases, will hinder future discovery of bioactivities and affect the establishment of future dietary guidelines if steps are not taken to overcome these issues. In order to resolve this situation, a nomenclature system for phenolic catabolites and their human phase II metabolites is proposed in this article and the basis of its format outlined. Previous names used in the literature are cited along with the recommended nomenclature, International Union of Pure and Applied Chemistry terminology, and, where appropriate, Chemical Abstracts Service numbers, InChIKey, and accurate mass. Oxford University Press 2020-09-16 /pmc/articles/PMC7528558/ /pubmed/32936878 http://dx.doi.org/10.1093/ajcn/nqaa204 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the American Society for Nutrition. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Special Article Kay, Colin D Clifford, Michael N Mena, Pedro McDougall, Gordon J Andres-Lacueva, Cristina Cassidy, Aedin Del Rio, Daniele Kuhnert, Nikolai Manach, Claudine Pereira-Caro, Gema Rodriguez-Mateos, Ana Scalbert, Augustin Tomás-Barberán, Francisco Williamson, Gary Wishart, David S Crozier, Alan Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites |
title | Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites |
title_full | Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites |
title_fullStr | Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites |
title_full_unstemmed | Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites |
title_short | Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites |
title_sort | recommendations for standardizing nomenclature for dietary (poly)phenol catabolites |
topic | Special Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528558/ https://www.ncbi.nlm.nih.gov/pubmed/32936878 http://dx.doi.org/10.1093/ajcn/nqaa204 |
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