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Safety of vaccines administration in hereditary fructose intolerance

Patients with hereditary fructose intolerance need to follow a life-long fructose dietary and drug restriction to prevent symptoms of intoxication. Concerns about vaccines administration have been manifested overtime, for the risk of a life-threatening acute intoxication. For this reason, at Ospedal...

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Autores principales: Maiorana, Arianna, Sabia, Antonella, Corsetti, Tiziana, Dionisi-Vici, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528578/
https://www.ncbi.nlm.nih.gov/pubmed/33004052
http://dx.doi.org/10.1186/s13023-020-01552-z
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author Maiorana, Arianna
Sabia, Antonella
Corsetti, Tiziana
Dionisi-Vici, Carlo
author_facet Maiorana, Arianna
Sabia, Antonella
Corsetti, Tiziana
Dionisi-Vici, Carlo
author_sort Maiorana, Arianna
collection PubMed
description Patients with hereditary fructose intolerance need to follow a life-long fructose dietary and drug restriction to prevent symptoms of intoxication. Concerns about vaccines administration have been manifested overtime, for the risk of a life-threatening acute intoxication. For this reason, at Ospedale Pediatrico Bambino Gesù we performed a deepen research from open sources, datasheets and Pharmaceutical Companies informations from the most common Italian and European vaccines, which are carried out in infancy and childhood. As a safe threshold of 2.4 mg/kg/dose was recently established for oral and parenteral (other than i.v.) route, the manuscript clarifies the safe administration of majority of vaccines in patients with hereditary fructose intolerance.
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spelling pubmed-75285782020-10-02 Safety of vaccines administration in hereditary fructose intolerance Maiorana, Arianna Sabia, Antonella Corsetti, Tiziana Dionisi-Vici, Carlo Orphanet J Rare Dis Letter to the Editor Patients with hereditary fructose intolerance need to follow a life-long fructose dietary and drug restriction to prevent symptoms of intoxication. Concerns about vaccines administration have been manifested overtime, for the risk of a life-threatening acute intoxication. For this reason, at Ospedale Pediatrico Bambino Gesù we performed a deepen research from open sources, datasheets and Pharmaceutical Companies informations from the most common Italian and European vaccines, which are carried out in infancy and childhood. As a safe threshold of 2.4 mg/kg/dose was recently established for oral and parenteral (other than i.v.) route, the manuscript clarifies the safe administration of majority of vaccines in patients with hereditary fructose intolerance. BioMed Central 2020-10-01 /pmc/articles/PMC7528578/ /pubmed/33004052 http://dx.doi.org/10.1186/s13023-020-01552-z Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Letter to the Editor
Maiorana, Arianna
Sabia, Antonella
Corsetti, Tiziana
Dionisi-Vici, Carlo
Safety of vaccines administration in hereditary fructose intolerance
title Safety of vaccines administration in hereditary fructose intolerance
title_full Safety of vaccines administration in hereditary fructose intolerance
title_fullStr Safety of vaccines administration in hereditary fructose intolerance
title_full_unstemmed Safety of vaccines administration in hereditary fructose intolerance
title_short Safety of vaccines administration in hereditary fructose intolerance
title_sort safety of vaccines administration in hereditary fructose intolerance
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528578/
https://www.ncbi.nlm.nih.gov/pubmed/33004052
http://dx.doi.org/10.1186/s13023-020-01552-z
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