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Peroxiredoxin 3 Has Important Roles on Arsenic Trioxide Induced Apoptosis in Human Acute Promyelocytic Leukemia Cell Line via Hyperoxidation of Mitochondrial Specific Reactive Oxygen Species

NB4 cell, the human acute promyelocytic leukemia (APL) cell line, was treated with various concentrations of arsenic trioxide (ATO) to induce apoptosis, measured by staining with 7-amino-actinomycin D (7-AAD) by flow cytometry. 2’, 7’-dichlorodihydro-fluorescein-diacetate (DCF-DA) and MitoSOX(TM) Re...

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Detalles Bibliográficos
Autores principales: Mun, Yeung-Chul, Ahn, Jee Young, Yoo, Eun Sun, Lee, Kyoung Eun, Nam, Eun Mi, Huh, Jungwon, Woo, Hyun Ae, Rhee, Sue Goo, Seong, Chu Myong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528683/
https://www.ncbi.nlm.nih.gov/pubmed/32975211
http://dx.doi.org/10.14348/molcells.2020.2234