Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation

Cancer cells must adapt metabolism to thrive despite nutrient limitations in the tumor microenvironment. In this issue of Genes & Development, King and colleagues (pp. 1345–1358) report a role for transcriptional regulators of the Hippo pathway to facilitate protein scavenging and support prolif...

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Detalles Bibliográficos
Autores principales: Sivanand, Sharanya, Vander Heiden, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Outlook
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528698/
https://www.ncbi.nlm.nih.gov/pubmed/33004484
http://dx.doi.org/10.1101/gad.343632.120
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author Sivanand, Sharanya
Vander Heiden, Matthew G.
author_facet Sivanand, Sharanya
Vander Heiden, Matthew G.
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collection PubMed
description Cancer cells must adapt metabolism to thrive despite nutrient limitations in the tumor microenvironment. In this issue of Genes & Development, King and colleagues (pp. 1345–1358) report a role for transcriptional regulators of the Hippo pathway to facilitate protein scavenging and support proliferation under some nutrient-deprived conditions.
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spelling pubmed-75286982021-04-01 Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation Sivanand, Sharanya Vander Heiden, Matthew G. Genes Dev Outlook Cancer cells must adapt metabolism to thrive despite nutrient limitations in the tumor microenvironment. In this issue of Genes & Development, King and colleagues (pp. 1345–1358) report a role for transcriptional regulators of the Hippo pathway to facilitate protein scavenging and support proliferation under some nutrient-deprived conditions. Cold Spring Harbor Laboratory Press 2020-10-01 /pmc/articles/PMC7528698/ /pubmed/33004484 http://dx.doi.org/10.1101/gad.343632.120 Text en © 2020 Sivanand and Vander Heiden; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Outlook
Sivanand, Sharanya
Vander Heiden, Matthew G.
Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation
title Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation
title_full Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation
title_fullStr Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation
title_full_unstemmed Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation
title_short Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation
title_sort transcriptional activation of macropinocytosis by the hippo pathway following nutrient limitation
topic Outlook
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528698/
https://www.ncbi.nlm.nih.gov/pubmed/33004484
http://dx.doi.org/10.1101/gad.343632.120
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