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A most formidable arsenal: genetic technologies for building a better mouse

The mouse is one of the most widely used model organisms for genetic study. The tools available to alter the mouse genome have developed over the preceding decades from forward screens to gene targeting in stem cells to the recent influx of CRISPR approaches. In this review, we first consider the hi...

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Detalles Bibliográficos
Autores principales: Clark, James F., Dinsmore, Colin J., Soriano, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528699/
https://www.ncbi.nlm.nih.gov/pubmed/33004485
http://dx.doi.org/10.1101/gad.342089.120

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