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SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability

Atypical teratoid rhabdoid tumors (ATRTs) are challenging pediatric brain cancers that are predominantly associated with inactivation of the gene SMARCB1, a conserved subunit of the chromatin remodeling BAF complex, which has known contributions to developmental processes. To identify potential inte...

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Detalles Bibliográficos
Autores principales: Parisian, Alison D., Koga, Tomoyuki, Miki, Shunichiro, Johann, Pascal D., Kool, Marcel, Crawford, John R., Furnari, Frank B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528703/
https://www.ncbi.nlm.nih.gov/pubmed/32912900
http://dx.doi.org/10.1101/gad.339978.120