Cargando…
SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability
Atypical teratoid rhabdoid tumors (ATRTs) are challenging pediatric brain cancers that are predominantly associated with inactivation of the gene SMARCB1, a conserved subunit of the chromatin remodeling BAF complex, which has known contributions to developmental processes. To identify potential inte...
Autores principales: | Parisian, Alison D., Koga, Tomoyuki, Miki, Shunichiro, Johann, Pascal D., Kool, Marcel, Crawford, John R., Furnari, Frank B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528703/ https://www.ncbi.nlm.nih.gov/pubmed/32912900 http://dx.doi.org/10.1101/gad.339978.120 |
Ejemplares similares
-
IL-1 TERT PROMOTER C228T MUTATION IN NEURAL PROGENITORS CONFERS GROWTH ADVANTAGE FOLLOWING TELOMERE SHORTENING IN VIVO
por: Furnari, Frank, et al.
Publicado: (2022) -
HGG-12. HUMAN IPSC-DERIVED H3.3K27M NEUROSPHERES: A NOVEL MODEL FOR INVESTIGATING DIPG PATHOGENESIS AND DRUG RESPONSE
por: Skinner, Kasey, et al.
Publicado: (2021) -
Beyond SMARCB1 Loss: Recent Insights into the Pathobiology of Epithelioid Sarcoma
por: Del Savio, Elisa, et al.
Publicado: (2022) -
Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases
por: Holdhof, Dörthe, et al.
Publicado: (2020) -
Gene of the month: SMARCB1
por: Kalimuthu, Sangeetha N, et al.
Publicado: (2016)