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COVID-19 and Cancer: Current Challenges and Perspectives

Patients with cancer have been disproportionately affected by the COVID-19 pandemic. This effect has included the adverse outcomes in patients with cancer who develop COVID-19, the impact of the COVID-19 pandemic on the delivery of cancer care, and the severe disruption to cancer research. However,...

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Autores principales: Bakouny, Ziad, Hawley, Jessica E., Choueiri, Toni K., Peters, Solange, Rini, Brian I., Warner, Jeremy L., Painter, Corrie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528740/
https://www.ncbi.nlm.nih.gov/pubmed/33049215
http://dx.doi.org/10.1016/j.ccell.2020.09.018
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author Bakouny, Ziad
Hawley, Jessica E.
Choueiri, Toni K.
Peters, Solange
Rini, Brian I.
Warner, Jeremy L.
Painter, Corrie A.
author_facet Bakouny, Ziad
Hawley, Jessica E.
Choueiri, Toni K.
Peters, Solange
Rini, Brian I.
Warner, Jeremy L.
Painter, Corrie A.
author_sort Bakouny, Ziad
collection PubMed
description Patients with cancer have been disproportionately affected by the COVID-19 pandemic. This effect has included the adverse outcomes in patients with cancer who develop COVID-19, the impact of the COVID-19 pandemic on the delivery of cancer care, and the severe disruption to cancer research. However, patients with cancer are a heterogeneous population, and recent studies have now documented factors that allow risk stratification of patients with cancer in order to optimize care. In this review, we highlight data at the intersection of COVID-19 and cancer, including the biological interplay between the two diseases and practical recommendations for the treatment of patients with cancer during the pandemic. We additionally discuss the potential long-lasting impact of the pandemic on cancer care due to its deleterious effect on cancer research, as well as biological insights from the cancer research community that could help develop novel therapies for all patients with COVID-19.
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spelling pubmed-75287402020-10-02 COVID-19 and Cancer: Current Challenges and Perspectives Bakouny, Ziad Hawley, Jessica E. Choueiri, Toni K. Peters, Solange Rini, Brian I. Warner, Jeremy L. Painter, Corrie A. Cancer Cell Review Patients with cancer have been disproportionately affected by the COVID-19 pandemic. This effect has included the adverse outcomes in patients with cancer who develop COVID-19, the impact of the COVID-19 pandemic on the delivery of cancer care, and the severe disruption to cancer research. However, patients with cancer are a heterogeneous population, and recent studies have now documented factors that allow risk stratification of patients with cancer in order to optimize care. In this review, we highlight data at the intersection of COVID-19 and cancer, including the biological interplay between the two diseases and practical recommendations for the treatment of patients with cancer during the pandemic. We additionally discuss the potential long-lasting impact of the pandemic on cancer care due to its deleterious effect on cancer research, as well as biological insights from the cancer research community that could help develop novel therapies for all patients with COVID-19. Elsevier Inc. 2020-11-09 2020-10-01 /pmc/articles/PMC7528740/ /pubmed/33049215 http://dx.doi.org/10.1016/j.ccell.2020.09.018 Text en © 2020 Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Bakouny, Ziad
Hawley, Jessica E.
Choueiri, Toni K.
Peters, Solange
Rini, Brian I.
Warner, Jeremy L.
Painter, Corrie A.
COVID-19 and Cancer: Current Challenges and Perspectives
title COVID-19 and Cancer: Current Challenges and Perspectives
title_full COVID-19 and Cancer: Current Challenges and Perspectives
title_fullStr COVID-19 and Cancer: Current Challenges and Perspectives
title_full_unstemmed COVID-19 and Cancer: Current Challenges and Perspectives
title_short COVID-19 and Cancer: Current Challenges and Perspectives
title_sort covid-19 and cancer: current challenges and perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528740/
https://www.ncbi.nlm.nih.gov/pubmed/33049215
http://dx.doi.org/10.1016/j.ccell.2020.09.018
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