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Thrombotic complications of COVID-19

INTRODUCTION: The novel coronavirus disease of 2019 (COVID-19) is associated with significant morbidity and mortality. The impact of thrombotic complications has been increasingly recognized as an important component of this disease. OBJECTIVE: This narrative review summarizes the thrombotic complic...

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Detalles Bibliográficos
Autores principales: Avila, Jacob, Long, Brit, Holladay, Dallas, Gottlieb, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528743/
https://www.ncbi.nlm.nih.gov/pubmed/33036855
http://dx.doi.org/10.1016/j.ajem.2020.09.065
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author Avila, Jacob
Long, Brit
Holladay, Dallas
Gottlieb, Michael
author_facet Avila, Jacob
Long, Brit
Holladay, Dallas
Gottlieb, Michael
author_sort Avila, Jacob
collection PubMed
description INTRODUCTION: The novel coronavirus disease of 2019 (COVID-19) is associated with significant morbidity and mortality. The impact of thrombotic complications has been increasingly recognized as an important component of this disease. OBJECTIVE: This narrative review summarizes the thrombotic complications associated with COVID-19 with an emphasis on information for Emergency Medicine clinicians. DISCUSSION: Thrombotic complications from COVID-19 are believed to be due to a hyperinflammatory response caused by the virus. Several complications have been described in the literature. These include acute limb ischemia, abdominal and thoracic aortic thrombosis, mesenteric ischemia, myocardial infarction, venous thromboembolism, acute cerebrovascular accident, and disseminated intravascular coagulation. CONCLUSION: It is important for Emergency Medicine clinicians to be aware of the thrombotic complications of COVID-19. Knowledge of these components are essential to rapidly recognize and treat to reduce morbidity and mortality in these patients.
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spelling pubmed-75287432020-10-02 Thrombotic complications of COVID-19 Avila, Jacob Long, Brit Holladay, Dallas Gottlieb, Michael Am J Emerg Med Article INTRODUCTION: The novel coronavirus disease of 2019 (COVID-19) is associated with significant morbidity and mortality. The impact of thrombotic complications has been increasingly recognized as an important component of this disease. OBJECTIVE: This narrative review summarizes the thrombotic complications associated with COVID-19 with an emphasis on information for Emergency Medicine clinicians. DISCUSSION: Thrombotic complications from COVID-19 are believed to be due to a hyperinflammatory response caused by the virus. Several complications have been described in the literature. These include acute limb ischemia, abdominal and thoracic aortic thrombosis, mesenteric ischemia, myocardial infarction, venous thromboembolism, acute cerebrovascular accident, and disseminated intravascular coagulation. CONCLUSION: It is important for Emergency Medicine clinicians to be aware of the thrombotic complications of COVID-19. Knowledge of these components are essential to rapidly recognize and treat to reduce morbidity and mortality in these patients. Elsevier Inc. 2021-01 2020-10-01 /pmc/articles/PMC7528743/ /pubmed/33036855 http://dx.doi.org/10.1016/j.ajem.2020.09.065 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Avila, Jacob
Long, Brit
Holladay, Dallas
Gottlieb, Michael
Thrombotic complications of COVID-19
title Thrombotic complications of COVID-19
title_full Thrombotic complications of COVID-19
title_fullStr Thrombotic complications of COVID-19
title_full_unstemmed Thrombotic complications of COVID-19
title_short Thrombotic complications of COVID-19
title_sort thrombotic complications of covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528743/
https://www.ncbi.nlm.nih.gov/pubmed/33036855
http://dx.doi.org/10.1016/j.ajem.2020.09.065
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