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Prior cardiovascular risk and screening echocardiograms predict hospitalization and severity of coronavirus infection among elderly medicare patients

BACKGROUND: The COVID-19 pandemic has disproportionally impacted the elderly. In the United States and Europe the mortality rate of elderly patients with COVID-19 is greater than 30%. Our aim is to determine predictors of COVID-19 related hospitalization and severity of disease among elderly Medicar...

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Autores principales: Ghany, Reyan, Palacio, Ana, Chen, Gordon, Dawkins, Elissa, McCarter, Daniel, Forbes, Emancia, Chung, Brian, Tamariz, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528840/
https://www.ncbi.nlm.nih.gov/pubmed/33024960
http://dx.doi.org/10.1016/j.ajpc.2020.100090
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author Ghany, Reyan
Palacio, Ana
Chen, Gordon
Dawkins, Elissa
McCarter, Daniel
Forbes, Emancia
Chung, Brian
Tamariz, Leonardo
author_facet Ghany, Reyan
Palacio, Ana
Chen, Gordon
Dawkins, Elissa
McCarter, Daniel
Forbes, Emancia
Chung, Brian
Tamariz, Leonardo
author_sort Ghany, Reyan
collection PubMed
description BACKGROUND: The COVID-19 pandemic has disproportionally impacted the elderly. In the United States and Europe the mortality rate of elderly patients with COVID-19 is greater than 30%. Our aim is to determine predictors of COVID-19 related hospitalization and severity of disease among elderly Medicare patients in the United States. METHODS: We conducted a retrospective cohort study including elderly Medicare COVID-19 patients across eight states. We collected data from the inpatient and outpatient electronic health record, demographic, clinical and echocardiographic predictors. Our primary outcomes were hospitalization and adult respiratory distress syndrome (ARDS). Our secondary outcome was mortality. RESULTS: We identified 400 COVID-19 positive patients (incidence 5.2; (95% CI 4.7–5.7) per 1000 patients). The mean age of our patients was 72 ​± ​8, 60% were female, 82% were minorities and had a mean Charlson score of 2.9 ​± ​1.4. Two-hundred and forty-four patients were hospitalized due to COVID-19 (63%) and the mortality rate was 18%; 95% CI 14–22 with 1 patient still in the hospital. Age, socioeconomic status, Charlson score, systolic blood pressure, body mass index, grade 2 or 3 diastolic dysfunction, moderate or severe left ventricular hypertrophy were significant predictors of hospitalization and ARDS (p ​< ​0.05). CONCLUSIONS: Our study reports a lower incidence on a COVID-19 cohort than previously reported. Predictors of poor outcomes included socio-economic, cardiovascular risk and echocardiographic measures. High touch care with early cardiovascular risk factor modification could explain the low risk of events in our population.
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spelling pubmed-75288402020-10-02 Prior cardiovascular risk and screening echocardiograms predict hospitalization and severity of coronavirus infection among elderly medicare patients Ghany, Reyan Palacio, Ana Chen, Gordon Dawkins, Elissa McCarter, Daniel Forbes, Emancia Chung, Brian Tamariz, Leonardo Am J Prev Cardiol Original Research BACKGROUND: The COVID-19 pandemic has disproportionally impacted the elderly. In the United States and Europe the mortality rate of elderly patients with COVID-19 is greater than 30%. Our aim is to determine predictors of COVID-19 related hospitalization and severity of disease among elderly Medicare patients in the United States. METHODS: We conducted a retrospective cohort study including elderly Medicare COVID-19 patients across eight states. We collected data from the inpatient and outpatient electronic health record, demographic, clinical and echocardiographic predictors. Our primary outcomes were hospitalization and adult respiratory distress syndrome (ARDS). Our secondary outcome was mortality. RESULTS: We identified 400 COVID-19 positive patients (incidence 5.2; (95% CI 4.7–5.7) per 1000 patients). The mean age of our patients was 72 ​± ​8, 60% were female, 82% were minorities and had a mean Charlson score of 2.9 ​± ​1.4. Two-hundred and forty-four patients were hospitalized due to COVID-19 (63%) and the mortality rate was 18%; 95% CI 14–22 with 1 patient still in the hospital. Age, socioeconomic status, Charlson score, systolic blood pressure, body mass index, grade 2 or 3 diastolic dysfunction, moderate or severe left ventricular hypertrophy were significant predictors of hospitalization and ARDS (p ​< ​0.05). CONCLUSIONS: Our study reports a lower incidence on a COVID-19 cohort than previously reported. Predictors of poor outcomes included socio-economic, cardiovascular risk and echocardiographic measures. High touch care with early cardiovascular risk factor modification could explain the low risk of events in our population. Elsevier 2020-10-01 /pmc/articles/PMC7528840/ /pubmed/33024960 http://dx.doi.org/10.1016/j.ajpc.2020.100090 Text en © 2020 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research
Ghany, Reyan
Palacio, Ana
Chen, Gordon
Dawkins, Elissa
McCarter, Daniel
Forbes, Emancia
Chung, Brian
Tamariz, Leonardo
Prior cardiovascular risk and screening echocardiograms predict hospitalization and severity of coronavirus infection among elderly medicare patients
title Prior cardiovascular risk and screening echocardiograms predict hospitalization and severity of coronavirus infection among elderly medicare patients
title_full Prior cardiovascular risk and screening echocardiograms predict hospitalization and severity of coronavirus infection among elderly medicare patients
title_fullStr Prior cardiovascular risk and screening echocardiograms predict hospitalization and severity of coronavirus infection among elderly medicare patients
title_full_unstemmed Prior cardiovascular risk and screening echocardiograms predict hospitalization and severity of coronavirus infection among elderly medicare patients
title_short Prior cardiovascular risk and screening echocardiograms predict hospitalization and severity of coronavirus infection among elderly medicare patients
title_sort prior cardiovascular risk and screening echocardiograms predict hospitalization and severity of coronavirus infection among elderly medicare patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528840/
https://www.ncbi.nlm.nih.gov/pubmed/33024960
http://dx.doi.org/10.1016/j.ajpc.2020.100090
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