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Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice

Synthetic mRNA represents an exciting cancer vaccine technology for the implementation of effective cancer immunotherapy. However, inefficient in vivo mRNA delivery along with a requirement for immune co-stimulation present major hurdles to achieving anti-tumor therapeutic efficacy. Here, we demonst...

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Detalles Bibliográficos
Autores principales:	Islam, Mohammad Ariful, Rice, Jamie, Reesor, Emma, Zope, Harshal, Tao, Wei, Lim, Michael, Ding, Jianxun, Chen, Yunhan, Aduluso, Dike, Zetter, Bruce R., Farokhzad, Omid C., Shi, Jinjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528902/ https://www.ncbi.nlm.nih.gov/pubmed/33099060 http://dx.doi.org/10.1016/j.biomaterials.2020.120431

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