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Heyde Syndrome Complicated by a Dieulafoy Lesion
Background: Heyde syndrome, a triad of aortic stenosis, von Willebrand factor deficiency, and gastrointestinal (GI) bleeding from angiodysplasia, is a disease of the elderly. A Dieulafoy lesion, a specific type of angiodysplasia, is a large, tortuous, submucosal end artery that penetrates through th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Division of Ochsner Clinic Foundation
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529123/ https://www.ncbi.nlm.nih.gov/pubmed/33071670 http://dx.doi.org/10.31486/toj.19.0072 |
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author | Noor, Abdullah Abadco, Dustin |
author_facet | Noor, Abdullah Abadco, Dustin |
author_sort | Noor, Abdullah |
collection | PubMed |
description | Background: Heyde syndrome, a triad of aortic stenosis, von Willebrand factor deficiency, and gastrointestinal (GI) bleeding from angiodysplasia, is a disease of the elderly. A Dieulafoy lesion, a specific type of angiodysplasia, is a large, tortuous, submucosal end artery that penetrates through the gastric mucosa and can cause life-threatening GI bleeding. We present a case of Heyde syndrome complicated by a Dieulafoy lesion. Case Report: A 72-year-old female presented with GI bleeding evidenced by black tarry stool for 7 days. Hemoglobin (Hgb) level was as low as 6.0 g/dL. Double-balloon enteroscopy (DBE) revealed 2 jejunal angiodysplasias that were treated with argon plasma coagulation. The patient continued to have dark stools after discharge. Repeat complete blood count showed Hgb of 6.2 g/dL, and repeat DBE showed a 1-mm focus of active bleeding in the proximal jejunum consistent with a Dieulafoy lesion. The lesion was successfully treated with argon plasma at 1 L/min and 25 watts. At follow-up 1 year later, the patient had had no GI bleeding symptoms since discharge. Conclusion: This case adds evidence that a Dieulafoy lesion is a potential complication of Heyde syndrome. Dieulafoy lesions can be life-threatening, so documenting occurrences that are complications of Heyde syndrome is important because of the potential for an increasing incidence of Heyde syndrome in the aging population. |
format | Online Article Text |
id | pubmed-7529123 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Academic Division of Ochsner Clinic Foundation |
record_format | MEDLINE/PubMed |
spelling | pubmed-75291232020-10-15 Heyde Syndrome Complicated by a Dieulafoy Lesion Noor, Abdullah Abadco, Dustin Ochsner J Case Reports and Clinical Observations Background: Heyde syndrome, a triad of aortic stenosis, von Willebrand factor deficiency, and gastrointestinal (GI) bleeding from angiodysplasia, is a disease of the elderly. A Dieulafoy lesion, a specific type of angiodysplasia, is a large, tortuous, submucosal end artery that penetrates through the gastric mucosa and can cause life-threatening GI bleeding. We present a case of Heyde syndrome complicated by a Dieulafoy lesion. Case Report: A 72-year-old female presented with GI bleeding evidenced by black tarry stool for 7 days. Hemoglobin (Hgb) level was as low as 6.0 g/dL. Double-balloon enteroscopy (DBE) revealed 2 jejunal angiodysplasias that were treated with argon plasma coagulation. The patient continued to have dark stools after discharge. Repeat complete blood count showed Hgb of 6.2 g/dL, and repeat DBE showed a 1-mm focus of active bleeding in the proximal jejunum consistent with a Dieulafoy lesion. The lesion was successfully treated with argon plasma at 1 L/min and 25 watts. At follow-up 1 year later, the patient had had no GI bleeding symptoms since discharge. Conclusion: This case adds evidence that a Dieulafoy lesion is a potential complication of Heyde syndrome. Dieulafoy lesions can be life-threatening, so documenting occurrences that are complications of Heyde syndrome is important because of the potential for an increasing incidence of Heyde syndrome in the aging population. Academic Division of Ochsner Clinic Foundation 2020 2020 /pmc/articles/PMC7529123/ /pubmed/33071670 http://dx.doi.org/10.31486/toj.19.0072 Text en ©2020 by the author(s); Creative Commons Attribution License (CC BY) http://creativecommons.org/licenses/by/4.0/legalcode ©2020 by the author(s); licensee Ochsner Journal, Ochsner Clinic Foundation, New Orleans, LA. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (creativecommons.org/licenses/by/4.0/legalcode) that permits unrestricted use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. |
spellingShingle | Case Reports and Clinical Observations Noor, Abdullah Abadco, Dustin Heyde Syndrome Complicated by a Dieulafoy Lesion |
title | Heyde Syndrome Complicated by a Dieulafoy Lesion |
title_full | Heyde Syndrome Complicated by a Dieulafoy Lesion |
title_fullStr | Heyde Syndrome Complicated by a Dieulafoy Lesion |
title_full_unstemmed | Heyde Syndrome Complicated by a Dieulafoy Lesion |
title_short | Heyde Syndrome Complicated by a Dieulafoy Lesion |
title_sort | heyde syndrome complicated by a dieulafoy lesion |
topic | Case Reports and Clinical Observations |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529123/ https://www.ncbi.nlm.nih.gov/pubmed/33071670 http://dx.doi.org/10.31486/toj.19.0072 |
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