Cytomegalovirus retinitis associated with high CD4 counts and DHEA abuse

The most frequent ocular manifestation of acquired immunodeficiency syndrome (AIDS) is cytomegalovirus retinitis (CMVR). This infection is reportedly inversely proportional to the CD4 counts. Usually CMVR develops once the CD4 counts fall below 50/mm(3). Our case report documents an AIDS patient who...

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Detalles Bibliográficos
Autores principales: Keat, Gan Yuen, Ahmad, Syed Shoeb, Subramaniam, Suresh, Ghani, Shuaibah Abdul, Samsudin, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529169/
https://www.ncbi.nlm.nih.gov/pubmed/33062999
http://dx.doi.org/10.4103/ijstd.IJSTD_90_15
Descripción
Sumario:The most frequent ocular manifestation of acquired immunodeficiency syndrome (AIDS) is cytomegalovirus retinitis (CMVR). This infection is reportedly inversely proportional to the CD4 counts. Usually CMVR develops once the CD4 counts fall below 50/mm(3). Our case report documents an AIDS patient who developed CMVR despite CD4 counts being persistently >200/mm(3). The patient was self-administering dehydroepiandrosterone, high dose Vitamin C, testosterone and hydrocortisone. This case report describes a unique case of pharmacologically induced elevated CD4 counts, which however, did not prevent the development of CMVR in the patient.

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